Everything about Biological Activity totally explained
Pharmacological or
biological activity is an expression describing the beneficial or adverse effects of a
drug on
living matter. When the drug is a complex chemical mixture, this activity is exerted by the substance's
active ingredient or
pharmacophore but can be modified by the other constituents. The main kind of biological activity is a substance's
toxicity. Activity is generally
dosage-dependent and it isn't uncommon to have effects ranging from beneficial to adversefor one substance when going from low to high doses. Activity depends critically on fulfillment of the
ADME criteria.
Whereas a material is considered bioactive if it has interaction with or effect on any
cell tissue in the
human body, pharmacological activity is usually taken to describe beneficial effects, for example the effects of
drug candidates.
In the study of
biomineralisation, bioactivity is often meant as the formation of
calcium phosphate deposits on the surface of objects placed in
simulated body fluid, a
buffer solution with ion content similar to
blood.
Further Information
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